I think the lines get very, very blurry in nWoD in terms of 'what you are playing'.
There's very little 'setting' at all really when you get down to it. Sure the splats describe other NPC monsters, or some political structures... but there's no 'Bad guys own New York! Flying monkeys pooping acid are swarming over Africa!' going on in the background. There's nothing to anchor you to the world.
oWoD was about being X, in a world where ABC and D were happening. ABC and D happening narrowed your path a bit and forced you to react to it.
nWoD is about being X. But there's no set ABC and D happening on the side so there's no focus, nothing outside of your own desire to drive your character in any direction.
For example, lets say you're Wally, a Red Talon werewolf in oWoD. You're a killer deep down inside, beneath whatever you try to do with your 'mortal' life. In fact you find it hard to interact with people as your rage gets higher. You always have to be on your toes because the BSD are going to get you. Or the vampires. Or the other creatures. There's spirits coming out of the woodwork and the setting materials themselves tell you in black and white some of the hotspots in the world and provide you with a dire, immediate 'something' to either act against, for, or at least acknowledge.
Now you're playing Willy, a Blood Talon werewolf in nWoD. You're a fighter at heart. There's nothing really keeping you from living a mortal life. Even as your mojo gets stronger you only get a few minor penalties and people might eye you funny but you can still do whatever. Whatever you're doing boils down to what your pack is up to though. Unless you're packless, in which case you might be a taxi driver. Or a stripper. Or maybe you hang out on the corner flinging shit at traffic like a homeless person. There's nothing keeping you from it. The only threats to you are those invented by yourself or the person directly running your chronicle.
On the topic of renown? You're going to earn it in oWoD. There's threats to face. It's not a matter of going out and seeking it; the trouble will come to you. System-aside (requiring player votes to earn is.. inconvenient in a MUSH) renown in nWoD feels more like something you have to go a-questing for.
In oWoD you're standing on the castle wall, firing arrows down at the invading barbarian hordes.
In nWoD, you're a knight errant. If you want to find danger you have to go seek it out for yourself.
Sorry for rambling.