Location, Location, Location: Where Do You Want to See Games?
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Here's some background from a certain point of view.
After the Roman Empire was split into two, the Easter Roman Empire had Constantinople as its capital whose name was derived from Constantine the Great. For most of that reign it was simply referred to as The City ("Η Πόλις").
After that point, and over time, it was increasingly 'roman' in only name - the Empire's official language was greek and its culture was a hybrid between hellenic and latin. It didn't quite experience the Dark Ages in the same way western Europe (arts and letters were still alive for a vast duration of its nearly thousand-year reign) did although it was still really brutal; if anyone feels like it, take a look at [the Nika riots](https://en.wikipedia.org/wiki/Nika_riots. Few shits were given about slaughtering a few thousands of their own citizens.
During its decline Constantinople was sacked twice; once in 1204 by Christians during the Crusade (who did far more damage to christian artifacts by carrying off and melting treasures to sell their gold than muslim Turks ever did later on - they famously brought mules into the Hagia Sofia to carry precious murals and heavy pieces of art out) although it was reclaimed by the remnants of Byzantium's Empire, although in a severely weakened state until it finally fell to the Ottoman Empire in 1453.
As for the current name, "Istambul" is derived from the Greek phrase "Εις Την Πόλιν" ('in the City') which is how citizens referred to it.
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@Bobotron oh a Roman historical like city Ala the Vampire Chronicles. Personally I'd mix it with the Anita Blake where vampires can be out and clash with police the supernatural laws/codes and rites, changing human laws to deal with new status of supernatural (some as citizens).
That kind of play, would be amazing.
Perhaps a city both lost to time (things old supernatural might find familar) but also Internet and TV.
I always loved the opening portion of "The Vampire Lestat" and "The Queen of the Damned" for their talk how ohow Lester moved and dealt with his own time, and then discovered the 80s.