@A-B It's sounding like there are a lot of concerns and complications for you about this endeavor.
Time zone issues are tough, but on a large enough game you may be able to find a decent crew of US nightowls or early risers. The problem with this is that large games are not at all common, and the number of them seems to be shrinking steadily year by year. RPIs apparently trend larger, so if you're looking into that, you may have better luck there also.
This is likely going to sound harsher than I intend, but it's something I feel needs to be made abundantly clear. I have major social anxiety, general anxiety, and long term major depression, so I'm not speaking in a cavalier way about something I don't understand, or don't have long term personal experience coping with.
What you seem to be seeking from whatever game you ultimately find is not going to be the answer. In a normal phase of human history, you would be very lucky to find a game that satisfies the need for interaction brought on by isolation. It is nor the responsibility of any game on the internet to provide the emotional support and resources, or an alternative, to prevent or change social isolation.
There's a lot to this, because while you may not be expecting a new cadre of besties or someone to play emotional support lifeline or counselor, you have: repeatedly outlined things you feel staff should have done based on your emotional needs and isolation; repeatedly claimed they should have overlooked, excused, or forgiven based on these things. These things are also not OK.
You ask for empathy and forgiveness, you don't ask for a free pass and insist they did it all wrong and it's so unfair based on your circumstances, you do not ask them to make special rules or change their existing rules or practices to suit you, and while you have done so politely in my estimation through this thread, you have done this consistently.
That is not how this works.
It is especially not how it works in this period of worldwide WTF. People who have zero experience with isolation are already struggling, and I have a genuine non-snark concern that if you talk about how you're in one of these spaces to escape RL isolation and expect some indulgence on the part of staff or other players because of a combination of anxiety and isolation, you are going to get sledgehammered by people screaming, "Join the fucking club!" as it is something the vast majority are dealing with.
The only people I know of who are NOT dealing with it are even worse off, stocking shelves or in the health field, at major risk and subject to incredible if not outright insane circumstances. Plenty of them are right here in the hobby, and like all of us who are in various shades of lockdown, they're trying to engage in a little fun escapism in the tiny scraps of time life affords them to do so.
Everyone's nerves are fried, and Gany put it far better than I could: these games have their own low thrum of steady stress. It is considerably worse right now. Looking for relief from isolation on these games is something that seems like common sense in a lockdown -- temporary or as a part of normal life for any given person -- but it isn't the easy solution it may seem, and that's in a normal time. You're less likely, right now, to get the kind of empathy and understanding you seem to be looking for because everyone's so stressed and screwed.