@Cupcake It is still #2 on my list of 'if I do a thing... ' Pirates first, if I can get my oomph back some day. But yeah. Low focus on the tech, high focus on the story for the characters, with a smattering of weirdness and mysticism that gets all the weirder when it comes into contact with the mysteries of the universe. Grid would have been oddly easy -- the caravan of ships themselves -- with a 'landing site of the week/month/whichever' as a room or two of a world that could be redesced as needed for wherever they were doing their schtick for the crowd.
Would have likely been super niche, but for the kind of stories that would exist in a world like that, I think a small crowd that works together well and has reason to get invested in everybody else as much as possible and had to work together as much as possible would have actually helped create the best vibe for it as a game on the whole.