I didn't want to derail another thread but someone mentioned in the RPG Systems thread of using a 'WoD Lite' type system. So that made me curious, what systems would be decent alternatives to WoD?
My TT group really enjoyed Everlasting. We house ruled some stuff but we found it more functional than WoD in a lot of ways.
When I was in High School my group loved Nightlife. Again, not perfect but very easy to mod and fairly balanced if I remember correctly.
There's also Urban Shadows and Monster Hearts but I'm not sure how well Powered by the Apocalypse would work on a MUX. Part of me says wonderfully...another part says not so much.
There's also Buffy/Angel, which hopefully we'll be seeing soon enough how well that works, but Eden Studios also offers Armageddon which can be modded to do modern nights quite well.
Then there are the systems that are so-called generic; GURPS, Savage Worlds, Genesys, and HERO. I think Savage Worlds could work well. In fact I've been close to doing a Ravenloft game using SW several times. I think Genesys could work well too but I'm less familiar.
Anyway, those are the systems I can think off of the top of my head that might work well as WoD alternates.