@DnvnQuinn
Who me? Push racism/specesism to its limit? I kid; the original game did heavily imply this, but here's one of the things I want to do:
Take whatever your genetic makeup is. Choose a metahuman trope from one of them. Dwarves? How about Biloko? Troll or Oni? How about something besides frickin' Elves? (Which are mostly Scandinavian et al. anyway)
While doing scant pre-research on this, I had a vision of Shadowrun with no metahumans, just humans. The vision was pretty glorious, but I don't think that would quite be Shadowrun, but I want a world that breaks out of Tolkeinrun. I want to push culture, creed, neighborhood, and the personal as a grand opposition to any future without choice.