Wtf did my double post turn into a single post. That is annoying.
Anyways what I was TRYING to say is that I usually look at wikis on my Macbook, which has a resolution of 1440x900, but I also sometimes look on my phone. When I was building my last wiki, I put mobile-friendliness towards the top of my list when considering skins and eventually settled on one built to be responsive from the ground up. I'm not a particularly fancy designer, but I do feel like I did a good job doing clean template layouts that was easy to read across devices. Also, when I was feeling particularly stressed about some other part of the wiki not fixing, I would sit and resize my browser for a while to enjoy the responsive design moving around. It's very soothing.