I meant to give a more serious response to this at some point and then forgot. But here goes.
Rule #1 - Love what you do.
If you don't have a passion for the project, then you will just be doing a job that at best you get a small sense of satisfaction for, at worst a large sent of resentment to the world AND a bill.
Rule #2 - Don't be afraid.
You can't please all of the people, all of the time. Don't be a capricious despot when you can help it, but don't be afraid to be firm. Or even to BE a despot when it is needed.
Rule #3 - It is not your life.
A lot of people define themselves by what they do for a living. Do not define yourself as staffer on a game. It is not your priority.
Rule #3.5 - It is just a game.
Nothing matters in the end. If someone is so worked up they are seriously, seriously upset about a game matter, tell them to chill the fuck out.
Rule #4 - People are fucked up, yo
Be prepared to deal with some of the most insidious, weird, petty, creepy shit. A lot of it will be he said she said. Have a plan, whether it just be a "don't talk to one another" or whatever.
Rule #5 - Sex.
Just assume it is happening