This one is from TTRPG; now that I've read the whole acronym and caught up with the rest of the class, you know.
Content warning: Drug Use.
***The Story***
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The GM had placed us in a situation where our almost-epic D&D characters ended up Somewhere Else, where we all thought we were just college students. So suddenly, my fighter is just a kid on a sports scholarship. But there were a few secrets and things to find on campus that could give you special abilities.
Someone is summoning some Lovecraftian horror on campus. We find the summoning. This giant tentacle thing is now rising up in the woods behind campus. We have like. 5 hit points.
Enter the Druggie. She had found one of those secrets. It seemed super lame. She could jump. Really high.
And she'd been charged with finding a few "supplies" for the druggie party later.
So she turns to the GM and says, "Welp. I have ecstasy and Everclear here in my inventory."
GM blinks slowly. "Uh, yes, you do."
"Great. So I mix the ecstasy in the Everclear, shake up the bottle, jump up, and throw the resulting mess into the creature's mouth."
The look on the GM's face was priceless.
Once he'd recovered, the thing loses its mind, wrecks its own summoning circle in its drug-fueled haze, and returns to whatever reality it was trying to emerge from.