My problem with Wrinkle was mainly about a particular plot point being written differently. Not because it was set someplace that wasn't in the book, and not even about the lack of Aunt Beast (I guess there's no real way to present her without coming across hokey and she became the Tom Bombadil of the film)...but the fundamental nature of a really important scene was changed, shifting the motivations of the characters, namely Meg and her father, in a way that makes the message very different.
Aesthetically the film is magnificent, the performances in and of themselves were lovely, with shout outs to my girl Rowan Blanchard (I miss Girl Meets World), and Gugu Mbatha-Raw and Hollywood Chris #2 have fantastic chemistry. And the collective stars/Misses were pretty great.