A reset would really do the game good I think.
Erase the pirate fiasco and all the other terrible displays of favoritism and issue with dinosaur characters and old equipment that got grand fathered in after rule changes.
Maybe make credits a little easier to come by so people don't have to literally spend 24 hours a day doing trading code for peanuts and spend months/years saving up for decent equipment. Also would present a chance to redo that skill list. 7 (7!) subskills for Run may be a little much.
Don't limit the cool ships so much? I remember there was only X number of type Y ship allowed in the game.. and almost all of them were owned by characters that hadn't logged in years. years. I started on Serenity maybe 5 years ago and there are some ships still parked where they were when I first logged in.
I started playing there after the worse of the staff favoritism, but caught a glimpse of it when Inara returned to throw Favor around. In that time between the game really was pretty awesome. A lot of that had to do with a great group of players running PRPs and the like, but the theme is good, a lot of the systems in place are pretty good.. it certainly has potential.